The United States Drug Enforcement Administration (DEA) maintains lists regarding the classification of illicit drugs (see DEA Schedules). It also maintains List I of chemicals and List II of chemicals, which contain chemicals that are used to manufacture the controlled substances/illicit drugs. The list is designated within the Controlled Substances Act, paragraphs 34 (list I) and 35 (list II) but can be modified by the U.S. Attorney General as illegal manufacturing practices change.
Although the list is controlled by the Attorney General, the list is considered a DEA list because the DEA publishes and enforces the list.
Suppliers of these products are subject to regulation and control measures:
RegulationList IList IITableting and Encapsulating MachinesSpecial Surveillance ListKnow your customerXXXXAnnual manufacturing, inventory, and use reports for bulk manufacturersXXX15 day advanced DEA notice required for imports, exports, and transshipmentsXX15 day advanced DEA notice required for international transactionsXXKeep transaction records for at least two yearsXXMaintain effective security controlsXXRequired reporting for unusual sales and losses or sales to DEA-identified companiesXXRegistration required for manufacturing, distribution, import, or exportXReports of mail-order sales to non-regulated entitiesX
List I chemicals These chemicals are designated as those that are used in the manufacture of the controlled substances and are important to the manufacture of the substances:
ChemicalIllicit drugAlpha-phenylacetoacetonitrile and its salts, optical isomers, and salts of optical isomers (APAAN)phenylacetone, methamphetamine, amphetamineAnthranilic acid, its esters, and its saltsmethaqualone and analoguesBenzyl cyanidephenylacetic acid, phenylacetone, amphetamineEphedrine, its salts, optical isomers, and salts of optical isomers methamphetamineErgonovine and its saltslysergic acid diethylamideErgotamine and its saltslysergic acid diethylamideN-Acetylanthranilic acid, its esters, and its saltsmethaqualoneNorpseudoephedrine, its salts, optical isomers, and salts of optical isomersamphetaminePhenylacetic acid, its esters, and its saltsphenylacetone, amphetamine, methamphetaminePhenylpropanolamine, its salts, optical isomers, and salts of optical isomersamphetamine, methamphetaminePiperidine and its saltsphencyclidine and analoguesPseudoephedrine, its salts, optical isomers, and salts of optical isomersmethamphetamine3,4-Methylenedioxyphenyl-2-propanoneMDMA, MDA, MDEA, MDOHMethylamine and its salts methamphetamineEthylamine and its saltsetilamfetaminePropionic anhydridefentanylIsosafroleMDMA, MDASafroleMDMA, MDAPiperonalMDMA, MDAN-Methylephedrine, its salts, optical isomers, and salts of optical isomers methamphetamineN-Methylpseudoephedrine, its salts, optical isomers, and salts of optical isomers methamphetamineHydroiodic acidmethamphetamine, amphetamineBenzaldehydemethamphetamine, amphetamineNitroethane methamphetamine, amphetamineGamma butyrolactone (other names include: GBL; dihydro-2(3H)-furanone; 1,2-butanolide; 1,4-butanolide; 4-hydroxybutanoic acid lactone; gamma-hydroxybutyric acid lactone) Gamma-Hydroxybutyric acid (GHB)Red phosphorusmethamphetamine, amphetamineWhite phosphorus (other names: yellow phosphorus)methamphetamine, amphetamineHypophosphorous acid and its salts (including ammonium hypophosphite, calcium hypophosphite, iron hypophosphite, potassium hypophosphite, manganese hypophosphite, magnesium hypophosphite and sodium hypophosphite) methamphetamine, amphetamineN-Phenethyl-4-piperidone (NPP)fentanylIodine methamphetamine, amphetamineErgocristine and its salts lysergic acid diethylamideN-(1-benzylpiperidin-4-yl)-N-phenylpropionamide (benzylfentanyl) and its saltsfentanylN-phenylpiperidin-4-amine(4-anilinopiperidine; N-phenyl-4-piperidinamine; 4-AP), its amides, its carbamates, and its saltsfentanyl3,4-MDP-2-P methyl glycidate (PMK glycidate) and its optical and geometric isomersMDMA and other "ecstasy"-type substances3,4-MDP-2-P methyl glycidic acid (PMK glycidic acid) and its salts, optical and geometric isomers, and salts of isomersMDMA and other "ecstasy"-type substancesAlpha-phenylacetoacetamide (APAA) and its optical isomersamphetamine, methamphetamineMethyl alpha-phenylacetoacetate (MAPA; methyl 3-oxo-2-phenylbutanoate) and its optical isomersphenylacetone, methamphetamine, amphetamine4-Piperidonefentanyl1-boc-4-AP (tert-butyl 4-(phenylamino)piperidine-1-carboxylate) and its saltsfentanyl
List II chemicals These chemicals are designated as those that are used in the manufacture of controlled substances:
Special Surveillance List Chemicals All listed chemicals as specified in 21 CFR 1310.02 (a) or (b). This includes supplements which contain a listed chemical, regardless of their dosage form or packaging and regardless of whether the chemical mixture, drug product or dietary supplement is exempt from regulatory controls. For each chemical, its illicit manufacturing use is given in parentheses. Some Special Surveillance List chemicals do not have an exclusive manufacturing use for a specific illicit drug but rather have a broad range of uses in both legitimate and illicit manufacturing operations.
ChemicalIllicit drugPhenyl-2-nitropropenesubstituted amphetamines1-(4-bromophenyl)propan-1-onesubstituted cathinones and substituted amphetamines1-(4-chlorophenyl)propan-1-onesubstituted cathinones and substituted amphetamines1-(4-methylphenyl)propan-1-onesubstituted cathinones and substituted amphetaminesCarbonyldiimidazoleLSD1,1-Dichloro-1-fluoroethanesolventN-benzyl-4-piperidonefentanylchloroephedrinemethamphetamineButyrophenonesubstituted cathinonesValerophenonesubstituted cathinonesPropiophenonesubstituted cathinones2C-H2C-x and DOx2-bromo-1-(4-chlorophenyl)propan-1-onesubstituted cathinones and substituted amphetamines2-bromo-1-(4-methoxyphenyl)propan-1-onesubstituted cathinones and substituted amphetamines2-bromo-1-(4-methylphenyl)propan-1-onesubstituted cathinones and substituted amphetamines2-bromo-1-phenylpentan-1-onesubstituted cathinones and substituted amphetamines2-bromo-1-phenylpropan-1-onesubstituted cathinones and substituted amphetaminesBMK glycidic acid and esters methamphetamine3-oxo-2-phenylbutanoic acid and its estersmethamphetamine3,4-methylenedioxyphenyl-2-nitropropene (MDP2NP)MDMAAmmonia gas amphetamine, methamphetamineAmmonium formate amphetamine, methamphetamineAzobisisobutyronitrileradical initiatorBromobenzene phencyclidine1,4-ButanediolGHB and Gamma-ButyrolactoneCyclohexanone phencyclidineDiethylamine and its salts lysergic acid diethylamideethyl 3-oxo-4-phenylbutanoatephenylacetoneethyl-3-(1,3-benzodioxol-5-yl)-2-methyloxirane-2-carboxylate (MDP2P ethyl glycidate)MDMAFormamideamphetamine, methamphetamineFormic acid amphetamine, methamphetamineLithium aluminum hydrideamphetamine, methamphetamineLithium metalamphetamine, methamphetamineMagnesium metal (turnings)phencyclidineMercuric chlorideamphetamine, methamphetaminemethyl 2-(1,3-benzodioxol-5-yl)-3-oxobutanoateMDMAN-Methylformamideamphetamine, methamphetamineOrganomagnesium halides (Grignard reagents) (e.g. ethylmagnesium bromide and phenylmagnesium bromide)phencyclidineortho-Toluidinemethaqualone2-Phenylethyl bromidefentanylPhenylethanolamine and its saltsPhosphorus pentachloridelysergic acid diethylamidePotassium dichromate general-purpose oxidizing agentPyridine and its saltsgeneral-purpose solventSodium borohydridereducing agentSodium dichromategeneral-purpose oxidizing agentSodium metalphenylacetoneSodium triacetoxyborohydridereducing agentpara-fluoro-1-boc-4-anilopiperidineparafluorofentanylThioglycolic acidmodafinilThionyl chloridelysergic acid diethylamideTrichloromonofluoromethane (aka freon-11, carrene-2)1,1,2-Trichloro-1,2,2-trifluoroethane (aka freon 113)
Equipment The equipment list:
22-liter heating mantles Encapsulating machines Hydrogenators Tableting machines, including punches and dies
See also Chemical Diversion and Trafficking Act Combat Methamphetamine Epidemic Act of 2005 Drug precursors European law on drug precursors
References
External links DEA Controlled Substance Schedules ()