There are multiple school districts in Lexington County, South Carolina.

Lexington County School District may refer to: Lexington County School District One, serving Lexington, Gilbert, and Pelion Lexington County School District Two, serving Cayce and West Columbia Lexington County School District Three, serving Batesburg-Leesville Lexington School District 4, serving Gaston and Swansea Lexington & Richland County School District Five, serving Chapin and Irmo