APN may refer to:

Biology and chemistry 3-Arylpropiolonitriles, a class of chemical reagents Acute pyelonephritis, a urinary tract infection Acyl peroxy nitrates, respiratory and eye irritants in photochemical smog

Computing Access Point Name, a gateway between mobile networks and frequently the Internet Apple Push Notification service Application-Layer Protocol Negotiation Algebraic Petri net, a kind of Petri net in computer science Amazon Partner Network, for Amazon Web Services

Journalism APN News & Media, an Australian and New Zealand media company Animal Planet (Australia and New Zealand), a television channel Novosti Press Agency (Agentstvo pechati Novosti), a Soviet news agency operating 1961–1990

Organizations African Parks Network, a private park management institution Alberta Playwrights Network, a professional association in Canada Americans for Peace Now, a group associated with the Israeli Peace Now movement Asia-Pacific Network for Global Change Research, in Kobe, Japan

Other Americanist phonetic notation, a system for phonetic transcription Advanced practice nurse, a nurse with post-graduate education in nursing Alpena County Regional Airport (IATA airport code) in Michigan Assessor's parcel number, to identify real property IOC code for alpinism at the Olympic Games