Vandamme is a surname. Notable people with the surname include:
Alexandre Vandamme (born 1962), Belgian businessman Dominique Vandamme (1770–1830), French military officer George Vandamme, Belgian wheelchair racer Jamaïque Vandamme (born 1985), Belgian footballer Michel Vandamme (1930–2019), French swimmer Virginie Vandamme (born 1966), French sprint canoeist