NF2, NF-2, or similar, may refer to:
Transportation De Havilland Venom NF.2, a British post-war night fighter aircraft Nickel & Foucard NF-2 Asterix, a French homebuilt aircraft
Biology Neurofibromatosis type II, an inherited disease Merlin (protein) or Neurofibromin 2, a cytoskeletal protein Nitrogen difluoride a chemical radical with formula •NF2