Acèrbi or Acerbi is an Italian surname. Notable people with the surname include:
Angelo Acerbi (born 1925), Italian Roman Catholic cardinal Francesco Acerbi (born 1988), Italian footballer Giovanni Acerbi (1825–1869), Italian soldier and politician Giuseppe Acerbi (1773–1846), Italian naturalist, explorer and composer Marco Acerbi (1949–1989), Italian hurdler Mario Acerbi (1913–2010), Italian professional football player Mario Acerbi (painter) (1887–1982), Italian painter
See also , an Italian warship Acerbis, Italian company Paolo Acerbis (b. 1981), Italian professional football player
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