James Patton may refer to:
James Patton (Virginia colonist) (1692–1755) Irish immigrant who lived in colonial Virginia James French Patton (1843–1882), American soldier and judge Jimmy Patton (1933–1972), American football player Jim Patton (brewer) (1953–2012), American anthropologist and craft beer brewer James L. Patton (born 1941), American mammalogist James Patton (defensive lineman) (born 1970), American football player James Patton (American football coach), American football player and coach James Patton (baseball), American baseball player James Patton (Mississippi politician) (1780–1830), lieutenant governor of Mississippi James D. Patton (1850–1925), American politician in the Virginia House of Delegates James Patton (Canadian politician) (1824–1888), Canadian lawyer and politician
See also James "Squire" Patton House, historic house in New Windsor, New York James Paton (disambiguation) James A. Patten (1852–1928), American financier and grain merchant