LSB may refer to:
Basketball Leagues Liga Sudamericana de Básquetbol, South America's prime international basketball league Liga Superior de Baloncesto, Cuba's top basketball league
Organisations Legal Services Board, independent body responsible for overseeing the regulation of lawyers in England and Wales Lending Standards Board, promote fair lending and increase consumer protection in the UK; by proactively monitoring and enforcing the Standards of Lending Practice. Lexington State Bank, a banking company based in Lexington, North Carolina Local services board (Ontario), local government in the Canadian province of Ontario Local Station Board, the elected governing body for each of the non-commercial, listener-supported Pacifica Radio stations in the United States. Lån & Spar Bank, a banking company based in Copenhagen, Denmark
Education Lavelle School for the Blind, school in New York City London School Board, former local government and education Luxembourg School of Business, a business school in Luxembourg Lyceum of Subic Bay, a college in the Philippines
Science, medicine and technology Lauryl tryptose broth, a biological selective medium Lower sideband, a band of frequencies in radio communications Long spine board, a device for casualty lifting and spine trauma prehospital care Low-surface-brightness galaxy, in astronomy Lysergic acid 2-butyl amide, a psychoactive compound related to LSD
Computing Least significant bit, the bit with the lowest significance in a word Least significant byte, the lowest byte in a multi-byte number Linux Standard Base, a standardisation project for Linux distributions
Other Lenguaje de Señas Bolivianas, Bolivian Sign Language Lutheran Service Book, hymnal for the Lutheran Church Legacy Standard Bible, revision of the NASB 1995 that uses Yahweh instead of LORD